BDBM50168860 4-(1-Ethyl-4-phenoxy-1H-imidazo[4,5-c]pyridin-2-yl)-furazan-3-ylamine::CHEMBL371391

SMILES: CCn1c(nc2c(Oc3ccccc3)nccc12)-c1nonc1N

InChI Key: InChIKey=IDWNTTNNMPLDJW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168860   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha 5 (Homo sapiens (Human))	BDBM50168860 (4-(1-Ethyl-4-phenoxy-1H-imidazo[4,5-c]pyridin-2-yl...) Show SMILES CCn1c(nc2c(Oc3ccccc3)nccc12)-c1nonc1N Show InChI InChI=1S/C16H14N6O2/c1-2-22-11-8-9-18-16(23-10-6-4-3-5-7-10)12(11)19-15(22)13-14(17)21-24-20-13/h3-9H,2H2,1H3,(H2,17,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory concentration against MSK-1				Bioorg Med Chem Lett 15: 3407-11 (2005) Article DOI: 10.1016/j.bmcl.2005.05.020 BindingDB Entry DOI: 10.7270/Q2S75FVN
					More data for this Ligand-Target Pair