new BindingDB logo
myBDB logout

BDBM50168863 4-(4-Ethoxy-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan-3-ylamine::CHEMBL188240

SMILES: CCOc1nccc2n(CC)c(nc12)-c1nonc1N

InChI Key: InChIKey=ATTRJLKUPUIICC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168863   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (human))
BDBM50168863
PNG
(4-(4-Ethoxy-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)...)
Show SMILES CCOc1nccc2n(CC)c(nc12)-c1nonc1N
Show InChI InChI=1S/C12H14N6O2/c1-3-18-7-5-6-14-12(19-4-2)8(7)15-11(18)9-10(13)17-20-16-9/h5-6H,3-4H2,1-2H3,(H2,13,17)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 174n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration against MSK-1


Bioorg Med Chem Lett 15: 3407-11 (2005)

More data for this
Ligand-Target Pair