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BDBM50168868 4-[1-(4-Amino-butyl)-1H-imidazo[4,5-c]pyridin-2-yl]-furazan-3-ylamine::CHEMBL363258

SMILES: NCCCCn1c(nc2cnccc12)-c1nonc1N

InChI Key: InChIKey=CNPSESFWJBPDDG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168868   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168868
PNG
(4-[1-(4-Amino-butyl)-1H-imidazo[4,5-c]pyridin-2-yl...)
Show SMILES NCCCCn1c(nc2cnccc12)-c1nonc1N
Show InChI InChI=1S/C12H15N7O/c13-4-1-2-6-19-9-3-5-15-7-8(9)16-12(19)10-11(14)18-20-17-10/h3,5,7H,1-2,4,6,13H2,(H2,14,18)
PDB
MMDB

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UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 13n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration against MSK-1


Bioorg Med Chem Lett 15: 3407-11 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.020
BindingDB Entry DOI: 10.7270/Q2S75FVN
More data for this
Ligand-Target Pair