BDBM50168870 4-(1-Ethyl-4-pyrrolidin-1-yl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan-3-ylamine::CHEMBL187985

SMILES: CCn1c(nc2c(nccc12)N1CCCC1)-c1nonc1N

InChI Key: InChIKey=XXTCPTVXBKEROM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha 5 (Homo sapiens (Human))	BDBM50168870 (4-(1-Ethyl-4-pyrrolidin-1-yl-1H-imidazo[4,5-c]pyri...) Show SMILES CCn1c(nc2c(nccc12)N1CCCC1)-c1nonc1N Show InChI InChI=1S/C14H17N7O/c1-2-21-9-5-6-16-13(20-7-3-4-8-20)10(9)17-14(21)11-12(15)19-22-18-11/h5-6H,2-4,7-8H2,1H3,(H2,15,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory concentration against MSK-1				Bioorg Med Chem Lett 15: 3407-11 (2005) Article DOI: 10.1016/j.bmcl.2005.05.020 BindingDB Entry DOI: 10.7270/Q2S75FVN
					More data for this Ligand-Target Pair