Found 6 hits for monomerid = 50169160 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Oligopeptide transporter, kidney isoform
(Rattus norvegicus) | BDBM50169160
((S)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)pr...)Show SMILES C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C14H17N3O3/c1-8(14(19)20)17-13(18)11(15)6-9-7-16-12-5-3-2-4-10(9)12/h2-5,7-8,11,16H,6,15H2,1H3,(H,17,18)(H,19,20)/t8-,11-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar AffyNet
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CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description Displacement of [14C]Gly-Sar from rat PEPT2 in SKPT0193 C1.2 cells |
J Med Chem 49: 4286-96 (2006)
Article DOI: 10.1021/jm0601811 BindingDB Entry DOI: 10.7270/Q2JM298V |
More data for this Ligand-Target Pair | |
Solute carrier family 15 member 2
(Homo sapiens (Human)) | BDBM50169160
((S)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)pr...)Show SMILES C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C14H17N3O3/c1-8(14(19)20)17-13(18)11(15)6-9-7-16-12-5-3-2-4-10(9)12/h2-5,7-8,11,16H,6,15H2,1H3,(H,17,18)(H,19,20)/t8-,11-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Milano
Curated by ChEMBL
| Assay Description Binding affinity to human PepT2 in SKTP cells |
Bioorg Med Chem 19: 4544-51 (2011)
Article DOI: 10.1016/j.bmc.2011.06.027 BindingDB Entry DOI: 10.7270/Q2MP549P |
More data for this Ligand-Target Pair | |
Oligopeptide transporter small intestine isoform
(Homo sapiens (Human)) | BDBM50169160
((S)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)pr...)Show SMILES C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C14H17N3O3/c1-8(14(19)20)17-13(18)11(15)6-9-7-16-12-5-3-2-4-10(9)12/h2-5,7-8,11,16H,6,15H2,1H3,(H,17,18)(H,19,20)/t8-,11-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description Binding affinity against membrane transport protein PEPT1 in human Caco-2 cells |
J Med Chem 48: 4410-9 (2005)
Article DOI: 10.1021/jm048982w BindingDB Entry DOI: 10.7270/Q2Q24116 |
More data for this Ligand-Target Pair | |
Oligopeptide transporter small intestine isoform
(Homo sapiens (Human)) | BDBM50169160
((S)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)pr...)Show SMILES C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C14H17N3O3/c1-8(14(19)20)17-13(18)11(15)6-9-7-16-12-5-3-2-4-10(9)12/h2-5,7-8,11,16H,6,15H2,1H3,(H,17,18)(H,19,20)/t8-,11-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description Displacement of [14C]Gly-Sar from human PEPT1 in Caco2 cells |
J Med Chem 49: 4286-96 (2006)
Article DOI: 10.1021/jm0601811 BindingDB Entry DOI: 10.7270/Q2JM298V |
More data for this Ligand-Target Pair | |
Oligopeptide transporter small intestine isoform
(Homo sapiens (Human)) | BDBM50169160
((S)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)pr...)Show SMILES C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C14H17N3O3/c1-8(14(19)20)17-13(18)11(15)6-9-7-16-12-5-3-2-4-10(9)12/h2-5,7-8,11,16H,6,15H2,1H3,(H,17,18)(H,19,20)/t8-,11-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells |
J Med Chem 49: 3636-44 (2006)
Article DOI: 10.1021/jm0511029 BindingDB Entry DOI: 10.7270/Q2P55P9R |
More data for this Ligand-Target Pair | |
Oligopeptide transporter small intestine isoform
(Homo sapiens (Human)) | BDBM50169160
((S)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)pr...)Show SMILES C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C14H17N3O3/c1-8(14(19)20)17-13(18)11(15)6-9-7-16-12-5-3-2-4-10(9)12/h2-5,7-8,11,16H,6,15H2,1H3,(H,17,18)(H,19,20)/t8-,11-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a |
Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Activation of human PEPT1 expressed in MDCK cells |
J Med Chem 49: 3636-44 (2006)
Article DOI: 10.1021/jm0511029 BindingDB Entry DOI: 10.7270/Q2P55P9R |
More data for this Ligand-Target Pair | |