null
SMILES: Clc1cc(Cl)cc(NC(=O)NCC2(CCN(CC2)C2CCC2)c2ccc(cc2)-c2cccc(c2)C#N)c1
InChI Key: InChIKey=JLTYJPDCKDVYCX-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50169381 (1-[4-(3'-Cyano-biphenyl-4-yl)-1-cyclobutyl-piperid...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL | Assay Description Ability to displace [125-I]-MCH()0.5 nM from human MCH1R(2.5 uM) expressed in CHO cells | Bioorg Med Chem Lett 15: 3696-700 (2005) Article DOI: 10.1016/j.bmcl.2005.05.085 BindingDB Entry DOI: 10.7270/Q2ZS2W16 | |||||||||||
More data for this Ligand-Target Pair |