BDBM50169383 CHEMBL178549::N-[4-(3'-Cyano-biphenyl-4-yl)-1-methyl-piperidin-4-ylmethyl]-2-(3,5-dichloro-phenyl)-acetamide

SMILES: CN1CCC(CNC(=O)Cc2cc(Cl)cc(Cl)c2)(CC1)c1ccc(cc1)-c1cccc(c1)C#N

InChI Key: InChIKey=JHQDXCQYPAJOOW-UHFFFAOYSA-N

Data: 1 KI

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50169383 (CHEMBL178549 | N-[4-(3'-Cyano-biphenyl-4-yl)-1-met...) Show SMILES CN1CCC(CNC(=O)Cc2cc(Cl)cc(Cl)c2)(CC1)c1ccc(cc1)-c1cccc(c1)C#N Show InChI InChI=1S/C28H27Cl2N3O/c1-33-11-9-28(10-12-33,19-32-27(34)16-21-14-25(29)17-26(30)15-21)24-7-5-22(6-8-24)23-4-2-3-20(13-23)18-31/h2-8,13-15,17H,9-12,16,19H2,1H3,(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	164	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL					Assay Description Ability to displace [125-I]-MCH()0.5 nM from human MCH1R(2.5 uM) expressed in CHO cells				Bioorg Med Chem Lett 15: 3696-700 (2005) Article DOI: 10.1016/j.bmcl.2005.05.085 BindingDB Entry DOI: 10.7270/Q2ZS2W16
					More data for this Ligand-Target Pair