BDBM50169454 CHEMBL188826::Thiophosphoric acid (R)-2-amino-2-[5-(4-octyl-phenyl)-1H-imidazol-2-yl]-ethyl ester; TFA
SMILES: CCCCCCCCc1ccc(cc1)-c1c[nH]c(n1)[C@@H](N)COP(O)(O)=S
InChI Key: InChIKey=JTZBCRHAPRTBAW-KRWDZBQOSA-N
Data: 4 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM50169454 (CHEMBL188826 | Thiophosphoric acid (R)-2-amino-2-[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Effective concentration against sphingosine-1-phosphate receptor 1 determined by a [c-35S]-GTP binding assay | Bioorg Med Chem Lett 15: 3568-72 (2005) Article DOI: 10.1016/j.bmcl.2005.05.097 BindingDB Entry DOI: 10.7270/Q2RF5VSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human)) | BDBM50169454 (CHEMBL188826 | Thiophosphoric acid (R)-2-amino-2-[...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 690 | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Effective concentration against sphingosine 1-phosphate receptor 3 determined by a [c-35S]-GTP binding assay | Bioorg Med Chem Lett 15: 3568-72 (2005) Article DOI: 10.1016/j.bmcl.2005.05.097 BindingDB Entry DOI: 10.7270/Q2RF5VSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human)) | BDBM50169454 (CHEMBL188826 | Thiophosphoric acid (R)-2-amino-2-[...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 29 | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Effective concentration against sphingosine 1-phosphate receptor 5 determined by a [c-35S]-GTP binding assay | Bioorg Med Chem Lett 15: 3568-72 (2005) Article DOI: 10.1016/j.bmcl.2005.05.097 BindingDB Entry DOI: 10.7270/Q2RF5VSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human)) | BDBM50169454 (CHEMBL188826 | Thiophosphoric acid (R)-2-amino-2-[...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Effective concentration against sphingosine 1-phosphate receptor 4 determined by a [c-35S]-GTP binding assay | Bioorg Med Chem Lett 15: 3568-72 (2005) Article DOI: 10.1016/j.bmcl.2005.05.097 BindingDB Entry DOI: 10.7270/Q2RF5VSG | |||||||||||
More data for this Ligand-Target Pair |