BDBM50169465 3-[4-(4-Amino-butyl)-5-quinolin-2-yl-4H-[1,2,4]triazol-3-ylsulfanyl]-1-(7-methyl-1H-indol-3-yl)-propan-1-one::CHEMBL434159
SMILES: Cc1cccc2c(c[nH]c12)C(=O)CCSc1nnc(-c2ccc3ccccc3n2)n1CCCCN
InChI Key: InChIKey=BLKXHWDWRVLQGN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Somatostatin receptor type 5 (Homo sapiens (Human)) | BDBM50169465 (3-[4-(4-Amino-butyl)-5-quinolin-2-yl-4H-[1,2,4]tri...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Inhibitory constant against human sst5 receptor at a dose of 10 uM | Bioorg Med Chem Lett 15: 3555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.061 BindingDB Entry DOI: 10.7270/Q2W66MH6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50169465 (3-[4-(4-Amino-butyl)-5-quinolin-2-yl-4H-[1,2,4]tri...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Inhibitory constant against human sst2 receptor at a dose of 10 uM | Bioorg Med Chem Lett 15: 3555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.061 BindingDB Entry DOI: 10.7270/Q2W66MH6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50169465 (3-[4-(4-Amino-butyl)-5-quinolin-2-yl-4H-[1,2,4]tri...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Binding affinity against human sst3 receptor at 10 uM | Bioorg Med Chem Lett 15: 3555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.061 BindingDB Entry DOI: 10.7270/Q2W66MH6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 1 (Homo sapiens (Human)) | BDBM50169465 (3-[4-(4-Amino-butyl)-5-quinolin-2-yl-4H-[1,2,4]tri...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Binding affinity against human sst1 receptor at a dose of 10 uM | Bioorg Med Chem Lett 15: 3555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.061 BindingDB Entry DOI: 10.7270/Q2W66MH6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50169465 (3-[4-(4-Amino-butyl)-5-quinolin-2-yl-4H-[1,2,4]tri...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Binding affinity against human sst4 receptor at a dose of 10 uM | Bioorg Med Chem Lett 15: 3555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.061 BindingDB Entry DOI: 10.7270/Q2W66MH6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 5 (Homo sapiens (Human)) | BDBM50169465 (3-[4-(4-Amino-butyl)-5-quinolin-2-yl-4H-[1,2,4]tri...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Inhibition of forskolin-induced cAMP accumulation in CHO-K1 cells expressing human sst5 receptor | Bioorg Med Chem Lett 15: 3555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.061 BindingDB Entry DOI: 10.7270/Q2W66MH6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50169465 (3-[4-(4-Amino-butyl)-5-quinolin-2-yl-4H-[1,2,4]tri...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Inhibition of forskolin-induced cAMP accumulation in CHO-K1 cells expressing human sst2 receptor | Bioorg Med Chem Lett 15: 3555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.061 BindingDB Entry DOI: 10.7270/Q2W66MH6 | |||||||||||
More data for this Ligand-Target Pair |