BDBM50169535 CHEMBL363592::Dipropyl-[2-trifluoromethyl-9-(2,4,6-trimethyl-phenyl)-9H-benzo[d]imidazo[1,2-a]imidazol-3-ylmethyl]-amine
SMILES: Cc1cc(C)c(c(C)c1)-n1c2ccccc2n2c(CN(CC3CC3)CC3CC3)c(nc12)C(F)(F)F
InChI Key: InChIKey=NNPQOYSAUKBOEH-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Corticotropin releasing factor receptor 1 (Homo sapiens (Human)) | BDBM50169535 (CHEMBL363592 | Dipropyl-[2-trifluoromethyl-9-(2,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity for human corticotropin releasing factor receptor 1 | Bioorg Med Chem Lett 15: 4029-32 (2005) Article DOI: 10.1016/j.bmcl.2005.06.028 BindingDB Entry DOI: 10.7270/Q2B27TS9 | |||||||||||
More data for this Ligand-Target Pair |