BDBM50169656 5-(2-Methyl-but-3-enoylamino)-thiazole-4-carboxylic acid thiazol-2-ylamide::CHEMBL359851

SMILES: CC(C=C)C(=O)Nc1scnc1C(=O)Nc1nccs1

InChI Key: InChIKey=NTZQHHLLIHUMMD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169656   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50169656 (5-(2-Methyl-but-3-enoylamino)-thiazole-4-carboxyli...) Show SMILES CC(C=C)C(=O)Nc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C12H12N4O2S2/c1-3-7(2)9(17)15-11-8(14-6-20-11)10(18)16-12-13-4-5-19-12/h3-7H,1H2,2H3,(H,15,17)(H,13,16,18)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Escherichia coli MetAP1 (150 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50169656 (5-(2-Methyl-but-3-enoylamino)-thiazole-4-carboxyli...) Show SMILES CC(C=C)C(=O)Nc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C12H12N4O2S2/c1-3-7(2)9(17)15-11-8(14-6-20-11)10(18)16-12-13-4-5-19-12/h3-7H,1H2,2H3,(H,15,17)(H,13,16,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair