BDBM50169675 5-(2-Pyrrolidin-1-yl-acetylamino)-thiazole-4-carboxylic acid thiazol-2-ylamide::CHEMBL178249

SMILES: O=C(CN1CCCC1)Nc1scnc1C(=O)Nc1nccs1

InChI Key: InChIKey=HLKRCJRWQUMSDX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50169675 (5-(2-Pyrrolidin-1-yl-acetylamino)-thiazole-4-carbo...) Show SMILES O=C(CN1CCCC1)Nc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C13H15N5O2S2/c19-9(7-18-4-1-2-5-18)16-12-10(15-8-22-12)11(20)17-13-14-3-6-21-13/h3,6,8H,1-2,4-5,7H2,(H,16,19)(H,14,17,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50169675 (5-(2-Pyrrolidin-1-yl-acetylamino)-thiazole-4-carbo...) Show SMILES O=C(CN1CCCC1)Nc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C13H15N5O2S2/c19-9(7-18-4-1-2-5-18)16-12-10(15-8-22-12)11(20)17-13-14-3-6-21-13/h3,6,8H,1-2,4-5,7H2,(H,16,19)(H,14,17,20)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Escherichia coli MetAP1 (150 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair