null

SMILES: Fc1ccc(cc1)C(=O)Nc1scnc1C(=O)Nc1nccs1

InChI Key: InChIKey=WDEUHKMVDWEXMO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169686   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase (Escherichia coli (strain K12))	BDBM50169686 (5-(4-Fluoro-benzoylamino)-thiazole-4-carboxylic ac...) Show SMILES Fc1ccc(cc1)C(=O)Nc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C14H9FN4O2S2/c15-9-3-1-8(2-4-9)11(20)18-13-10(17-7-23-13)12(21)19-14-16-5-6-22-14/h1-7H,(H,18,20)(H,16,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Escherichia coli MetAP1 (150 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50169686 (5-(4-Fluoro-benzoylamino)-thiazole-4-carboxylic ac...) Show SMILES Fc1ccc(cc1)C(=O)Nc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C14H9FN4O2S2/c15-9-3-1-8(2-4-9)11(20)18-13-10(17-7-23-13)12(21)19-14-16-5-6-22-14/h1-7H,(H,18,20)(H,16,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair