BDBM50169893 3-{5-[4-(4-Morpholin-4-yl-phenylamino)-[1,3,5]triazin-2-yl]-pyridin-3-ylamino}-propan-1-ol::CHEMBL191377

SMILES: OCCCNc1cncc(c1)-c1ncnc(Nc2ccc(cc2)N2CCOCC2)n1

InChI Key: InChIKey=RITLUZRZBLXNNE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169893   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50169893 (3-{5-[4-(4-Morpholin-4-yl-phenylamino)-[1,3,5]tria...) Show SMILES OCCCNc1cncc(c1)-c1ncnc(Nc2ccc(cc2)N2CCOCC2)n1 Show InChI InChI=1S/C21H25N7O2/c29-9-1-6-23-18-12-16(13-22-14-18)20-24-15-25-21(27-20)26-17-2-4-19(5-3-17)28-7-10-30-11-8-28/h2-5,12-15,23,29H,1,6-11H2,(H,24,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of cyclin dependent kinase (CDK1)				J Med Chem 48: 4535-46 (2005) Article DOI: 10.1021/jm040214h BindingDB Entry DOI: 10.7270/Q2833RK0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50169893 (3-{5-[4-(4-Morpholin-4-yl-phenylamino)-[1,3,5]tria...) Show SMILES OCCCNc1cncc(c1)-c1ncnc(Nc2ccc(cc2)N2CCOCC2)n1 Show InChI InChI=1S/C21H25N7O2/c29-9-1-6-23-18-12-16(13-22-14-18)20-24-15-25-21(27-20)26-17-2-4-19(5-3-17)28-7-10-30-11-8-28/h2-5,12-15,23,29H,1,6-11H2,(H,24,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of vascular endothelial growth factor receptor 2				J Med Chem 48: 4535-46 (2005) Article DOI: 10.1021/jm040214h BindingDB Entry DOI: 10.7270/Q2833RK0
					More data for this Ligand-Target Pair