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BDBM50169912 2,3-Dicyclohexyl-1-[2-(4-dimethylamino-piperidin-1-yl)-2-oxo-ethyl]-1H-indole-6-carboxylic acid::CHEMBL364941

SMILES: CN(C)C1CCN(CC1)C(=O)Cn1c(C2CCCCC2)c(C2CCCCC2)c2ccc(cc12)C(O)=O

InChI Key: InChIKey=UIQOIFPJTWFZTA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169912   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)		BDBM50169912
PNG
(2,3-Dicyclohexyl-1-[2-(4-dimethylamino-piperidin-1...)
Show SMILES CN(C)C1CCN(CC1)C(=O)Cn1c(C2CCCCC2)c(C2CCCCC2)c2ccc(cc12)C(O)=O
Show InChI InChI=1S/C30H43N3O3/c1-31(2)24-15-17-32(18-16-24)27(34)20-33-26-19-23(30(35)36)13-14-25(26)28(21-9-5-3-6-10-21)29(33)22-11-7-4-8-12-22/h13-14,19,21-22,24H,3-12,15-18,20H2,1-2H3,(H,35,36)
UniProtKB/TrEMBL

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Similars
Article
PubMed
n/an/a 72n/an/an/an/an/an/a



IRBM (Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against by hepatitis C virus NS5B polymerase

J Med Chem 48: 4547-57 (2005)


Article DOI: 10.1021/jm050056+
BindingDB Entry DOI: 10.7270/Q24B30VN
More data for this
Ligand-Target Pair