BDBM50169928 3-Cyclopentyl-1-[2-(4-methyl-piperazin-1-yl)-2-oxo-ethyl]-2-phenyl-1H-indole-6-carboxylic acid::CHEMBL189534

SMILES: CN1CCN(CC1)C(=O)Cn1c(c(C2CCCC2)c2ccc(cc12)C(O)=O)-c1ccccc1

InChI Key: InChIKey=KLCMBNUGKRFXJK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50169928 (3-Cyclopentyl-1-[2-(4-methyl-piperazin-1-yl)-2-oxo...) Show SMILES CN1CCN(CC1)C(=O)Cn1c(c(C2CCCC2)c2ccc(cc12)C(O)=O)-c1ccccc1 Show InChI InChI=1S/C27H31N3O3/c1-28-13-15-29(16-14-28)24(31)18-30-23-17-21(27(32)33)11-12-22(23)25(19-7-5-6-8-19)26(30)20-9-3-2-4-10-20/h2-4,9-12,17,19H,5-8,13-16,18H2,1H3,(H,32,33)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
IRBM (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against by hepatitis C virus NS5B polymerase				J Med Chem 48: 4547-57 (2005) Article DOI: 10.1021/jm050056+ BindingDB Entry DOI: 10.7270/Q24B30VN
					More data for this Ligand-Target Pair