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BDBM50169938 3-Cyclohexyl-1-[2-(4-dimethylamino-piperidin-1-yl)-2-oxo-ethyl]-2-phenyl-1H-indole-6-carboxylic acid::CHEMBL188218

SMILES: CN(CC1CCCN(C)C1)C(=O)Cn1c(c(C2CCCC2)c2ccc(cc12)C(O)=O)-c1ccccc1

InChI Key: InChIKey=JHYHVDRJIABSCO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169938   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)		BDBM50169938
PNG
(3-Cyclohexyl-1-[2-(4-dimethylamino-piperidin-1-yl)...)
Show SMILES CN(CC1CCCN(C)C1)C(=O)Cn1c(c(C2CCCC2)c2ccc(cc12)C(O)=O)-c1ccccc1
Show InChI InChI=1S/C30H37N3O3/c1-31-16-8-9-21(18-31)19-32(2)27(34)20-33-26-17-24(30(35)36)14-15-25(26)28(22-10-6-7-11-22)29(33)23-12-4-3-5-13-23/h3-5,12-15,17,21-22H,6-11,16,18-20H2,1-2H3,(H,35,36)
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 47n/an/an/an/an/an/a



IRBM (Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against by hepatitis C virus NS5B polymerase

J Med Chem 48: 4547-57 (2005)


Article DOI: 10.1021/jm050056+
BindingDB Entry DOI: 10.7270/Q24B30VN
More data for this
Ligand-Target Pair