BDBM50169954 (6aR,10aR)-3-Adamantan-2-ylmethyl-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol::AM-757::CHEMBL372866
SMILES: CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(CC3C4CC5CC(C4)CC3C5)cc1OC2(C)C
InChI Key: InChIKey=HWYQADZEUSGKLP-CASOXHBNSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 2 (MOUSE) | BDBM50169954 ((6aR,10aR)-3-Adamantan-2-ylmethyl-6,6,9-trimethyl-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 76 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Inhibition of [3H]CP-55,940 binding to cannabinoid receptor 2 of mouse spleen membranes | J Med Chem 48: 4576-85 (2005) Article DOI: 10.1021/jm058175c BindingDB Entry DOI: 10.7270/Q20K283W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50169954 ((6aR,10aR)-3-Adamantan-2-ylmethyl-6,6,9-trimethyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 76 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Binding affinity to CB2 receptor (unknown origin) | Bioorg Med Chem 17: 2598-606 (2009) Article DOI: 10.1016/j.bmc.2008.11.059 BindingDB Entry DOI: 10.7270/Q2DJ5FHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50169954 ((6aR,10aR)-3-Adamantan-2-ylmethyl-6,6,9-trimethyl-...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 79.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Binding affinity to CB1 receptor (unknown origin) | Bioorg Med Chem 17: 2598-606 (2009) Article DOI: 10.1016/j.bmc.2008.11.059 BindingDB Entry DOI: 10.7270/Q2DJ5FHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM50169954 ((6aR,10aR)-3-Adamantan-2-ylmethyl-6,6,9-trimethyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 79.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Inhibition of [3H]CP-55,940 binding to cannabinoid receptor 1 of rat brain | J Med Chem 48: 4576-85 (2005) Article DOI: 10.1021/jm058175c BindingDB Entry DOI: 10.7270/Q20K283W | |||||||||||
More data for this Ligand-Target Pair |