BDBM50169955 3-(2-Amino-ethyl)-5-[1-(4-ethoxy-phenyl)-meth-(Z)-ylidene]-thiazolidine-2,4-dione::3-(2-aminoethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione::CHEMBL363555
SMILES: CCOc1ccc(\C=C2/SC(=O)N(CCN)C2=O)cc1
InChI Key: InChIKey=NBJOUCGADPALIB-XFXZXTDPSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Mitogen-activated protein kinase 1 (Homo sapiens (Human)) | BDBM50169955 (3-(2-Amino-ethyl)-5-[1-(4-ethoxy-phenyl)-meth-(Z)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Dissociation constant for ERK2 kinase | J Med Chem 48: 4586-95 (2005) Article DOI: 10.1021/jm0501174 BindingDB Entry DOI: 10.7270/Q2VT1RNN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50169955 (3-(2-Amino-ethyl)-5-[1-(4-ethoxy-phenyl)-meth-(Z)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern Ohio Universities Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-B after 15 mins | Bioorg Med Chem Lett 20: 5295-8 (2010) Article DOI: 10.1016/j.bmcl.2010.06.128 BindingDB Entry DOI: 10.7270/Q2S46SX1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase (flavin-containing) A (Homo sapiens (Human)) | BDBM50169955 (3-(2-Amino-ethyl)-5-[1-(4-ethoxy-phenyl)-meth-(Z)-...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern Ohio Universities Colleges of Medicine and Pharmacy Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOA assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline by fluorimetry | Bioorg Med Chem Lett 21: 4798-803 (2011) Article DOI: 10.1016/j.bmcl.2011.06.060 BindingDB Entry DOI: 10.7270/Q2GX4CKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50169955 (3-(2-Amino-ethyl)-5-[1-(4-ethoxy-phenyl)-meth-(Z)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern Ohio Universities Colleges of Medicine and Pharmacy Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOB by amplex red assay | Bioorg Med Chem Lett 21: 4798-803 (2011) Article DOI: 10.1016/j.bmcl.2011.06.060 BindingDB Entry DOI: 10.7270/Q2GX4CKZ | |||||||||||
More data for this Ligand-Target Pair |