BDBM50170107 CHEMBL3806112
SMILES: Fc1cc(F)cc(Cc2ccc3[nH]nc(NC(=O)c4ccc(CN5CCCCC5)cc4NC4CCOCC4)c3c2)c1
InChI Key: InChIKey=QDOTUHIGOCRMSM-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Insulin receptor (Homo sapiens (Human)) | BDBM50170107 (CHEMBL3806112) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 653 | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences Srl Curated by ChEMBL | Assay Description Inhibition of IR (unknown origin) in presence of gamma33-ATP | J Med Chem 59: 3392-408 (2016) BindingDB Entry DOI: 10.7270/Q27M09TG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor I receptor (Homo sapiens (Human)) | BDBM50170107 (CHEMBL3806112) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 391 | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences Srl Curated by ChEMBL | Assay Description Inhibition of IGF1R (unknown origin) in presence of gamma33-ATP | J Med Chem 59: 3392-408 (2016) BindingDB Entry DOI: 10.7270/Q27M09TG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50170107 (CHEMBL3806112) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences Srl Curated by ChEMBL | Assay Description Inhibition of recombinant ALK (unknown origin) in presence of gamma33-ATP | J Med Chem 59: 3392-408 (2016) BindingDB Entry DOI: 10.7270/Q27M09TG | |||||||||||
More data for this Ligand-Target Pair |