BDBM50170144 CHEMBL188293::{2-[(E)-2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quinolin-7-yl}-pyridin-3-yl-methanone

SMILES: Oc1ccc(\C=C\c2ccc3ccc(C(=O)c4cccnc4)c(O)c3n2)cc1O

InChI Key: InChIKey=KOXMUIJVVUZLEA-XVNBXDOJSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50170144 (CHEMBL188293 | {2-[(E)-2-(3,4-Dihydroxy-phenyl)-vi...) Show SMILES Oc1ccc(\C=C\c2ccc3ccc(C(=O)c4cccnc4)c(O)c3n2)cc1O Show InChI InChI=1S/C23H16N2O4/c26-19-10-4-14(12-20(19)27)3-7-17-8-5-15-6-9-18(23(29)21(15)25-17)22(28)16-2-1-11-24-13-16/h1-13,26-27,29H/b7-3+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Unité Associée au CNRS Curated by ChEMBL					Assay Description In vitro inhibitory concentration against HIV-1 recombinant integrase activity in standard 3'-processing assay				Bioorg Med Chem Lett 15: 4019-22 (2005) Article DOI: 10.1016/j.bmcl.2005.06.036 BindingDB Entry DOI: 10.7270/Q2GM86VW
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50170144 (CHEMBL188293 | {2-[(E)-2-(3,4-Dihydroxy-phenyl)-vi...) Show SMILES Oc1ccc(\C=C\c2ccc3ccc(C(=O)c4cccnc4)c(O)c3n2)cc1O Show InChI InChI=1S/C23H16N2O4/c26-19-10-4-14(12-20(19)27)3-7-17-8-5-15-6-9-18(23(29)21(15)25-17)22(28)16-2-1-11-24-13-16/h1-13,26-27,29H/b7-3+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Unité Associée au CNRS Curated by ChEMBL					Assay Description In vitro inhibitory concentration against HIV-1 recombinant integrase activity in strand transfer assay				Bioorg Med Chem Lett 15: 4019-22 (2005) Article DOI: 10.1016/j.bmcl.2005.06.036 BindingDB Entry DOI: 10.7270/Q2GM86VW
					More data for this Ligand-Target Pair