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BDBM50170150 CHEMBL3806015

SMILES: N#C\N=C(\NCCOc1ccccc1)NC[C@@H]1CC[C@@H](C1)c1c[nH]cn1

InChI Key: InChIKey=GVJXRRRUZIKLHQ-CVEARBPZSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170150   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H1 receptor


(Homo sapiens (Human))		BDBM50170150
PNG
(CHEMBL3806015)
Show SMILES N#C\N=C(\NCCOc1ccccc1)NC[C@@H]1CC[C@@H](C1)c1c[nH]cn1 |r|
Show InChI InChI=1S/C19H24N6O/c20-13-24-19(22-8-9-26-17-4-2-1-3-5-17)23-11-15-6-7-16(10-15)18-12-21-14-25-18/h1-5,12,14-16H,6-11H2,(H,21,25)(H2,22,23,24)/t15-,16+/m1/s1
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Similars
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Displacement of [3H]mepyramine from human histamine H1 receptor expressed in sf9 cell membrane co-expressing RGS4 incubated for 60 mins by liquid sci...

J Med Chem 59: 3452-70 (2016)


BindingDB Entry DOI: 10.7270/Q23T9K42
More data for this
Ligand-Target Pair