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SMILES: Cc1c(F)cnc2[nH]c(=O)c(=O)[nH]c12

InChI Key: InChIKey=PGCLUISHINNHMT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50170227   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D-amino-acid oxidase (Homo sapiens (Human))	BDBM50170227 (CHEMBL3805642) Show SMILES Cc1c(F)cnc2[nH]c(=O)c(=O)[nH]c12 Show InChI InChI=1S/C8H6FN3O2/c1-3-4(9)2-10-6-5(3)11-7(13)8(14)12-6/h2H,1H3,(H,11,13)(H,10,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiao Tong University Curated by ChEMBL					Assay Description Inhibition of human recombinant DAAO using D-alanine as substrate assessed as pyruvate production incubated for 60 mins by microplate reader analysis				Eur J Med Chem 117: 19-32 (2016) BindingDB Entry DOI: 10.7270/Q2V989ZS
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM50170227 (CHEMBL3805642) Show SMILES Cc1c(F)cnc2[nH]c(=O)c(=O)[nH]c12 Show InChI InChI=1S/C8H6FN3O2/c1-3-4(9)2-10-6-5(3)11-7(13)8(14)12-6/h2H,1H3,(H,11,13)(H,10,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiao Tong University Curated by ChEMBL					Assay Description Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...				Eur J Med Chem 117: 19-32 (2016) BindingDB Entry DOI: 10.7270/Q2V989ZS
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Rattus norvegicus (rat))	BDBM50170227 (CHEMBL3805642) Show SMILES Cc1c(F)cnc2[nH]c(=O)c(=O)[nH]c12 Show InChI InChI=1S/C8H6FN3O2/c1-3-4(9)2-10-6-5(3)11-7(13)8(14)12-6/h2H,1H3,(H,11,13)(H,10,12,14)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiao Tong University Curated by ChEMBL					Assay Description Inhibition of rat spinal DAAO using D-alanine as substrate assessed as pyruvate production incubated for 60 mins by microplate reader analysis				Eur J Med Chem 117: 19-32 (2016) BindingDB Entry DOI: 10.7270/Q2V989ZS
					More data for this Ligand-Target Pair