BDBM50170234 CHEMBL329680
SMILES: Cc1c(Br)cnc2nc(O)c(O)nc12
InChI Key: InChIKey=CUEPJLKZPWHSHG-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50170234 (CHEMBL329680) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description In vitro binding affinity for glycine site on the NMDA receptor. | Citation and Details BindingDB Entry DOI: 10.7270/Q2CN762M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-Amino Acid Oxidase (DAAO) (Sus scrofa (pig)) | BDBM50170234 (CHEMBL329680) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Jiao Tong University Curated by ChEMBL | Assay Description Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade... | Eur J Med Chem 117: 19-32 (2016) BindingDB Entry DOI: 10.7270/Q2V989ZS | |||||||||||
More data for this Ligand-Target Pair |