BDBM50170262 CHEMBL190637::N-{4-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-3-chloro-phenyl}-methanesulfonamide
SMILES: CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2Cl)cc1
InChI Key: InChIKey=WIYJZLNIOBZPKQ-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vanilloid receptor (Rattus norvegicus (rat)) | BDBM50170262 (CHEMBL190637 | N-{4-[3-(4-tert-Butyl-benzyl)-thiou...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 45.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Antagonist activity for rat TRPV1 expressed in CHO cells | Bioorg Med Chem Lett 15: 4136-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.009 BindingDB Entry DOI: 10.7270/Q23B5ZN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vanilloid receptor (Rattus norvegicus (rat)) | BDBM50170262 (CHEMBL190637 | N-{4-[3-(4-tert-Butyl-benzyl)-thiou...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 144 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTX | Bioorg Med Chem Lett 15: 4136-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.009 BindingDB Entry DOI: 10.7270/Q23B5ZN0 | |||||||||||
More data for this Ligand-Target Pair |