BDBM50170282 CHEMBL3806131

SMILES: Cn1ncc(Cl)c1-c1csc(c1)C(=O)NC1(CCNCC1)c1ccc(F)cc1

InChI Key: InChIKey=MUBZXHWRHNPWGD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50170282 (CHEMBL3806131) Show SMILES Cn1ncc(Cl)c1-c1csc(c1)C(=O)NC1(CCNCC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H20ClFN4OS/c1-26-18(16(21)11-24-26)13-10-17(28-12-13)19(27)25-20(6-8-23-9-7-20)14-2-4-15(22)5-3-14/h2-5,10-12,23H,6-9H2,1H3,(H,25,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of Akt1 (unknown origin) expressed in Escherichia coli using peptide substrate after 1 hr by HTRF assay				Eur J Med Chem 117: 47-58 (2016) BindingDB Entry DOI: 10.7270/Q2QJ7K5K
					More data for this Ligand-Target Pair