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BDBM50170309 1-(2,2-Dimethyl-propyl)-4-propyl-5-[3-(1H-tetrazol-5-yl)-phenoxy]-1H-indole::CHEMBL363945

SMILES: CCCc1c(Oc2cccc(c2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)ccc12

InChI Key: InChIKey=GHSAXRFIIOGJNX-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170309   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50170309
PNG
(1-(2,2-Dimethyl-propyl)-4-propyl-5-[3-(1H-tetrazol...)
Show SMILES CCCc1c(Oc2cccc(c2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)ccc12
Show InChI InChI=1S/C23H27N5O/c1-5-7-19-18-12-13-28(15-23(2,3)4)20(18)10-11-21(19)29-17-9-6-8-16(14-17)22-24-26-27-25-22/h6,8-14H,5,7,15H2,1-4H3,(H,24,25,26,27)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 134n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr


Bioorg Med Chem Lett 15: 4068-72 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.017
BindingDB Entry DOI: 10.7270/Q2Q52P6K
More data for this
Ligand-Target Pair