BDBM50170311 1,4-Dipropyl-5-{4-[4-(1H-tetrazol-5-yl)-phenoxy]-butoxy}-1H-indole::CHEMBL191579

SMILES: CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CCC)ccc12

InChI Key: InChIKey=GXKOHQQCSSECNY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170311   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170311 (1,4-Dipropyl-5-{4-[4-(1H-tetrazol-5-yl)-phenoxy]-b...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CCC)ccc12 Show InChI InChI=1S/C25H31N5O2/c1-3-7-22-21-14-16-30(15-4-2)23(21)12-13-24(22)32-18-6-5-17-31-20-10-8-19(9-11-20)25-26-28-29-27-25/h8-14,16H,3-7,15,17-18H2,1-2H3,(H,26,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	652	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair