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SMILES: CC(C)(C)Cn1ccc2c(Br)c(OCCCCOc3ccc(cc3)-c3nnn[nH]3)ccc12

InChI Key: InChIKey=RRBFWLMWOFDFTC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170313   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM50170313
PNG
(4-Bromo-1-(2,2-dimethyl-propyl)-5-{4-[4-(1H-tetraz...)
Show SMILES CC(C)(C)Cn1ccc2c(Br)c(OCCCCOc3ccc(cc3)-c3nnn[nH]3)ccc12
Show InChI InChI=1S/C24H28BrN5O2/c1-24(2,3)16-30-13-12-19-20(30)10-11-21(22(19)25)32-15-5-4-14-31-18-8-6-17(7-9-18)23-26-28-29-27-23/h6-13H,4-5,14-16H2,1-3H3,(H,26,27,28,29)
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Article
PubMed
n/an/an/an/a 2.26E+3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr

Bioorg Med Chem Lett 15: 4068-72 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.017
BindingDB Entry DOI: 10.7270/Q2Q52P6K
More data for this
Ligand-Target Pair