BDBM50170324 1-Cyclohexylmethyl-4-propyl-5-{4-[4-(1H-tetrazol-5-yl)-phenoxy]-butoxy}-1H-indole::CHEMBL186018

SMILES: CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC3CCCCC3)ccc12

InChI Key: InChIKey=FTVHYJPUDBNLFI-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170324   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170324 (1-Cyclohexylmethyl-4-propyl-5-{4-[4-(1H-tetrazol-5...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC3CCCCC3)ccc12 Show InChI InChI=1S/C29H37N5O2/c1-2-8-26-25-17-18-34(21-22-9-4-3-5-10-22)27(25)15-16-28(26)36-20-7-6-19-35-24-13-11-23(12-14-24)29-30-32-33-31-29/h11-18,22H,2-10,19-21H2,1H3,(H,30,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	228	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair