BDBM50170326 1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetrazol-5-yl)-phenoxy]-butoxy}-1H-indole::CHEMBL185994

SMILES: CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)ccc12

InChI Key: InChIKey=UQVYMHBNVXRQRW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170326   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170326 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)ccc12 Show InChI InChI=1S/C27H35N5O2/c1-5-8-23-22-15-16-32(19-27(2,3)4)24(22)13-14-25(23)34-18-7-6-17-33-21-11-9-20(10-12-21)26-28-30-31-29-26/h9-16H,5-8,17-19H2,1-4H3,(H,28,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	559	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair