BDBM50170363 5-[2-(2-Chloro-phenyl)-2-methoxy-ethyl]-thiazole-4-carboxylic acid thiazol-2-ylamide::CHEMBL426802
SMILES: COC(Cc1scnc1C(=O)Nc1nccs1)c1ccccc1Cl
InChI Key: InChIKey=GTZFJTVJYAUUHN-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12)) | BDBM50170363 (5-[2-(2-Chloro-phenyl)-2-methoxy-ethyl]-thiazole-4...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Graduate School of the Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibitory concentration against EcMetAP1 enzyme activity | Bioorg Med Chem Lett 15: 4130-5 (2005) Article DOI: 10.1016/j.bmcl.2005.06.005 BindingDB Entry DOI: 10.7270/Q2FN15RH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine aminopeptidase 1 (Saccharomyces cerevisiae) | BDBM50170363 (5-[2-(2-Chloro-phenyl)-2-methoxy-ethyl]-thiazole-4...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Graduate School of the Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibitory concentration against ScMetAP1 enzyme activity | Bioorg Med Chem Lett 15: 4130-5 (2005) Article DOI: 10.1016/j.bmcl.2005.06.005 BindingDB Entry DOI: 10.7270/Q2FN15RH | |||||||||||
More data for this Ligand-Target Pair |