BDBM50170368 CHEMBL363875::Cyclopentanecarboxylic acid 2-[4-(thiazol-2-ylcarbamoyl)-thiazol-5-yl]-ethyl ester

SMILES: O=C(OCCc1scnc1C(=O)Nc1nccs1)C1CCCC1

InChI Key: InChIKey=JPSWNFMXBLRSIV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50170368 (CHEMBL363875 | Cyclopentanecarboxylic acid 2-[4-(t...) Show SMILES O=C(OCCc1scnc1C(=O)Nc1nccs1)C1CCCC1 Show InChI InChI=1S/C15H17N3O3S2/c19-13(18-15-16-6-8-22-15)12-11(23-9-17-12)5-7-21-14(20)10-3-1-2-4-10/h6,8-10H,1-5,7H2,(H,16,18,19)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration against ScMetAP1 enzyme activity				Bioorg Med Chem Lett 15: 4130-5 (2005) Article DOI: 10.1016/j.bmcl.2005.06.005 BindingDB Entry DOI: 10.7270/Q2FN15RH
					More data for this Ligand-Target Pair
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50170368 (CHEMBL363875 | Cyclopentanecarboxylic acid 2-[4-(t...) Show SMILES O=C(OCCc1scnc1C(=O)Nc1nccs1)C1CCCC1 Show InChI InChI=1S/C15H17N3O3S2/c19-13(18-15-16-6-8-22-15)12-11(23-9-17-12)5-7-21-14(20)10-3-1-2-4-10/h6,8-10H,1-5,7H2,(H,16,18,19)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration against EcMetAP1 enzyme activity				Bioorg Med Chem Lett 15: 4130-5 (2005) Article DOI: 10.1016/j.bmcl.2005.06.005 BindingDB Entry DOI: 10.7270/Q2FN15RH
					More data for this Ligand-Target Pair