BDBM50170380 Benzyloxy-acetic acid 2-[4-(thiazol-2-ylcarbamoyl)-thiazol-5-yl]-ethyl ester::CHEMBL189127

SMILES: O=C(COCc1ccccc1)OCCc1scnc1C(=O)Nc1nccs1

InChI Key: InChIKey=UVMFBMOBLUCTHK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170380   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50170380 (Benzyloxy-acetic acid 2-[4-(thiazol-2-ylcarbamoyl)...) Show SMILES O=C(COCc1ccccc1)OCCc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C18H17N3O4S2/c22-15(11-24-10-13-4-2-1-3-5-13)25-8-6-14-16(20-12-27-14)17(23)21-18-19-7-9-26-18/h1-5,7,9,12H,6,8,10-11H2,(H,19,21,23)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration against ScMetAP1 enzyme activity				Bioorg Med Chem Lett 15: 4130-5 (2005) Article DOI: 10.1016/j.bmcl.2005.06.005 BindingDB Entry DOI: 10.7270/Q2FN15RH
					More data for this Ligand-Target Pair
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50170380 (Benzyloxy-acetic acid 2-[4-(thiazol-2-ylcarbamoyl)...) Show SMILES O=C(COCc1ccccc1)OCCc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C18H17N3O4S2/c22-15(11-24-10-13-4-2-1-3-5-13)25-8-6-14-16(20-12-27-14)17(23)21-18-19-7-9-26-18/h1-5,7,9,12H,6,8,10-11H2,(H,19,21,23)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration against EcMetAP1 enzyme activity				Bioorg Med Chem Lett 15: 4130-5 (2005) Article DOI: 10.1016/j.bmcl.2005.06.005 BindingDB Entry DOI: 10.7270/Q2FN15RH
					More data for this Ligand-Target Pair