BDBM50170383 5-[2-(2-Fluoro-phenyl)-2-methoxy-ethyl]-thiazole-4-carboxylic acid thiazol-2-ylamide::CHEMBL189688

SMILES: COC(Cc1scnc1C(=O)Nc1nccs1)c1ccccc1F

InChI Key: InChIKey=NJHDXAQYKXSYJC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50170383 (5-[2-(2-Fluoro-phenyl)-2-methoxy-ethyl]-thiazole-4...) Show SMILES COC(Cc1scnc1C(=O)Nc1nccs1)c1ccccc1F Show InChI InChI=1S/C16H14FN3O2S2/c1-22-12(10-4-2-3-5-11(10)17)8-13-14(19-9-24-13)15(21)20-16-18-6-7-23-16/h2-7,9,12H,8H2,1H3,(H,18,20,21)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration against EcMetAP1 enzyme activity				Bioorg Med Chem Lett 15: 4130-5 (2005) Article DOI: 10.1016/j.bmcl.2005.06.005 BindingDB Entry DOI: 10.7270/Q2FN15RH
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50170383 (5-[2-(2-Fluoro-phenyl)-2-methoxy-ethyl]-thiazole-4...) Show SMILES COC(Cc1scnc1C(=O)Nc1nccs1)c1ccccc1F Show InChI InChI=1S/C16H14FN3O2S2/c1-22-12(10-4-2-3-5-11(10)17)8-13-14(19-9-24-13)15(21)20-16-18-6-7-23-16/h2-7,9,12H,8H2,1H3,(H,18,20,21)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration against ScMetAP1 enzyme activity				Bioorg Med Chem Lett 15: 4130-5 (2005) Article DOI: 10.1016/j.bmcl.2005.06.005 BindingDB Entry DOI: 10.7270/Q2FN15RH
					More data for this Ligand-Target Pair