BDBM50170418 CHEMBL3805006

SMILES: Cn1ncc(Cl)c1-c1ccc(cc1)C(=O)NC1(CCNCC1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=JHHJJSLGKHPTTC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170418   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50170418 (CHEMBL3805006) Show SMILES Cn1ncc(Cl)c1-c1ccc(cc1)C(=O)NC1(CCNCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H21Cl3N4O/c1-29-20(19(25)13-27-29)14-2-4-15(5-3-14)21(30)28-22(8-10-26-11-9-22)16-6-7-17(23)18(24)12-16/h2-7,12-13,26H,8-11H2,1H3,(H,28,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of Akt1 (unknown origin) expressed in Escherichia coli using peptide substrate after 1 hr by HTRF assay				Eur J Med Chem 117: 47-58 (2016) BindingDB Entry DOI: 10.7270/Q2QJ7K5K
					More data for this Ligand-Target Pair