BDBM50170422 CHEMBL3805443

SMILES: Cn1cc(cc1C(=O)NC1(CCNCC1)c1ccc(Cl)c(Cl)c1)-c1c(Br)cnn1C

InChI Key: InChIKey=OEJSKCNTFQFBPA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50170422 (CHEMBL3805443) Show SMILES Cn1cc(cc1C(=O)NC1(CCNCC1)c1ccc(Cl)c(Cl)c1)-c1c(Br)cnn1C Show InChI InChI=1S/C21H22BrCl2N5O/c1-28-12-13(19-15(22)11-26-29(19)2)9-18(28)20(30)27-21(5-7-25-8-6-21)14-3-4-16(23)17(24)10-14/h3-4,9-12,25H,5-8H2,1-2H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of Akt1 (unknown origin) expressed in Escherichia coli using peptide substrate after 1 hr by HTRF assay				Eur J Med Chem 117: 47-58 (2016) BindingDB Entry DOI: 10.7270/Q2QJ7K5K
					More data for this Ligand-Target Pair