BDBM50170615 3-(3-Chloro-4-fluoro-phenyl)-1-(3'-cyano-biphenyl-4-yl)-1-(2-methylamino-ethyl)-urea::CHEMBL189611
SMILES: CNCCN(C(=O)Nc1ccc(F)c(Cl)c1)c1ccc(cc1)-c1cccc(c1)C#N
InChI Key: InChIKey=OSTMRUJPPBVRRB-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanin-concentrating hormone receptor (Homo sapiens (Human)) | BDBM50170615 (3-(3-Chloro-4-fluoro-phenyl)-1-(3'-cyano-biphenyl-...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of human melanin concentrating hormone receptor 1 | J Med Chem 48: 4746-9 (2005) Article DOI: 10.1021/jm0503852 BindingDB Entry DOI: 10.7270/Q2P55N26 | |||||||||||
More data for this Ligand-Target Pair |