BDBM50170625 3-(3-Chloro-4-fluoro-phenyl)-1-(3'-cyano-biphenyl-4-yl)-1-(1-cyclopentyl-piperidin-4-yl)-urea::CHEMBL364162
SMILES: Fc1ccc(NC(=O)N(C2CCN(CC2)C2CCCC2)c2ccc(cc2)-c2cccc(c2)C#N)cc1Cl
InChI Key: InChIKey=NFZSAMALEWHITI-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanin-concentrating hormone receptor (Homo sapiens (Human)) | BDBM50170625 (3-(3-Chloro-4-fluoro-phenyl)-1-(3'-cyano-biphenyl-...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of human melanin concentrating hormone receptor 1 | J Med Chem 48: 4746-9 (2005) Article DOI: 10.1021/jm0503852 BindingDB Entry DOI: 10.7270/Q2P55N26 | |||||||||||
More data for this Ligand-Target Pair |