BDBM50170626 1-(3'-Cyano-biphenyl-4-yl)-1-(1-cyclopropylmethyl-piperidin-4-yl)-3-(4-fluoro-3-trifluoromethyl-phenyl)-urea::CHEMBL191409

SMILES: Fc1ccc(NC(=O)N(C2CCN(CC3CC3)CC2)c2ccc(cc2)-c2cccc(c2)C#N)cc1C(F)(F)F

InChI Key: InChIKey=GRQMCEOLOUOYLX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170626   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50170626 (1-(3'-Cyano-biphenyl-4-yl)-1-(1-cyclopropylmethyl-...) Show SMILES Fc1ccc(NC(=O)N(C2CCN(CC3CC3)CC2)c2ccc(cc2)-c2cccc(c2)C#N)cc1C(F)(F)F Show InChI InChI=1S/C30H28F4N4O/c31-28-11-8-24(17-27(28)30(32,33)34)36-29(39)38(26-12-14-37(15-13-26)19-20-4-5-20)25-9-6-22(7-10-25)23-3-1-2-21(16-23)18-35/h1-3,6-11,16-17,20,26H,4-5,12-15,19H2,(H,36,39)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of human melanin concentrating hormone receptor 1				J Med Chem 48: 4746-9 (2005) Article DOI: 10.1021/jm0503852 BindingDB Entry DOI: 10.7270/Q2P55N26
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