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SMILES: NCc1ccc(CNCC(N)P(O)(O)=O)cc1

InChI Key: InChIKey=PRJZGAQJDFCWMW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50170877   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Homo sapiens (Human))	BDBM50170877 (CHEMBL3804956) Show SMILES NCc1ccc(CNCC(N)P(O)(O)=O)cc1 Show InChI InChI=1S/C10H18N3O3P/c11-5-8-1-3-9(4-2-8)6-13-7-10(12)17(14,15)16/h1-4,10,13H,5-7,11-12H2,(H2,14,15,16)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...				Eur J Med Chem 117: 187-96 (2016) BindingDB Entry DOI: 10.7270/Q2BC41F8
					More data for this Ligand-Target Pair
Endoplasmic reticulum aminopeptidase 2 (Homo sapiens (Human))	BDBM50170877 (CHEMBL3804956) Show SMILES NCc1ccc(CNCC(N)P(O)(O)=O)cc1 Show InChI InChI=1S/C10H18N3O3P/c11-5-8-1-3-9(4-2-8)6-13-7-10(12)17(14,15)16/h1-4,10,13H,5-7,11-12H2,(H2,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of human ERAP2 preincubated for 30 to 60 mins followed by addition of Arg-AMC as substrate measured for 15 mins by spectrofluorimetric met...				Bioorg Med Chem Lett 26: 4122-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.062 BindingDB Entry DOI: 10.7270/Q2TT4SW1
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50170877 (CHEMBL3804956) Show SMILES NCc1ccc(CNCC(N)P(O)(O)=O)cc1 Show InChI InChI=1S/C10H18N3O3P/c11-5-8-1-3-9(4-2-8)6-13-7-10(12)17(14,15)16/h1-4,10,13H,5-7,11-12H2,(H2,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...				Eur J Med Chem 117: 187-96 (2016) BindingDB Entry DOI: 10.7270/Q2BC41F8
					More data for this Ligand-Target Pair
Cytosol aminopeptidase [33-68,L62W] (Sus scrofa (Pig))	BDBM50170877 (CHEMBL3804956) Show SMILES NCc1ccc(CNCC(N)P(O)(O)=O)cc1 Show InChI InChI=1S/C10H18N3O3P/c11-5-8-1-3-9(4-2-8)6-13-7-10(12)17(14,15)16/h1-4,10,13H,5-7,11-12H2,(H2,14,15,16)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.65E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of porcine kidney leucine aminopeptidase M17 using Leu-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition meas...				Eur J Med Chem 117: 187-96 (2016) BindingDB Entry DOI: 10.7270/Q2BC41F8
					More data for this Ligand-Target Pair
Endoplasmic reticulum aminopeptidase 1 (Homo sapiens (Human))	BDBM50170877 (CHEMBL3804956) Show SMILES NCc1ccc(CNCC(N)P(O)(O)=O)cc1 Show InChI InChI=1S/C10H18N3O3P/c11-5-8-1-3-9(4-2-8)6-13-7-10(12)17(14,15)16/h1-4,10,13H,5-7,11-12H2,(H2,14,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of human ERAP1 preincubated for 30 to 60 mins followed by addition of Leu-AMC as substrate measured for 15 mins by spectrofluorimetric met...				Bioorg Med Chem Lett 26: 4122-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.062 BindingDB Entry DOI: 10.7270/Q2TT4SW1
					More data for this Ligand-Target Pair