BDBM50170881 CHEMBL3805028

SMILES: CC(C)CNCC(N)P(O)(=O)CC(Cc1ccccc1)C(O)=O

InChI Key: InChIKey=WQCVTAYXCVGUSK-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50170881   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Homo sapiens (Human))	BDBM50170881 (CHEMBL3805028) Show SMILES CC(C)CNCC(N)P(O)(=O)CC(Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H27N2O4P/c1-12(2)9-18-10-15(17)23(21,22)11-14(16(19)20)8-13-6-4-3-5-7-13/h3-7,12,14-15,18H,8-11,17H2,1-2H3,(H,19,20)(H,21,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	499	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...				Eur J Med Chem 117: 187-96 (2016) BindingDB Entry DOI: 10.7270/Q2BC41F8
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50170881 (CHEMBL3805028) Show SMILES CC(C)CNCC(N)P(O)(=O)CC(Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H27N2O4P/c1-12(2)9-18-10-15(17)23(21,22)11-14(16(19)20)8-13-6-4-3-5-7-13/h3-7,12,14-15,18H,8-11,17H2,1-2H3,(H,19,20)(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	4.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...				Eur J Med Chem 117: 187-96 (2016) BindingDB Entry DOI: 10.7270/Q2BC41F8
					More data for this Ligand-Target Pair
Leucine aminopeptidase (LAP) (Sus scrofa (Pig))	BDBM50170881 (CHEMBL3805028) Show SMILES CC(C)CNCC(N)P(O)(=O)CC(Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H27N2O4P/c1-12(2)9-18-10-15(17)23(21,22)11-14(16(19)20)8-13-6-4-3-5-7-13/h3-7,12,14-15,18H,8-11,17H2,1-2H3,(H,19,20)(H,21,22)	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of porcine kidney leucine aminopeptidase M17 using Leu-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition meas...				Eur J Med Chem 117: 187-96 (2016) BindingDB Entry DOI: 10.7270/Q2BC41F8
					More data for this Ligand-Target Pair
Aminopeptidase (Homo sapiens (Human))	BDBM50170881 (CHEMBL3805028) Show SMILES CC(C)CNCC(N)P(O)(=O)CC(Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H27N2O4P/c1-12(2)9-18-10-15(17)23(21,22)11-14(16(19)20)8-13-6-4-3-5-7-13/h3-7,12,14-15,18H,8-11,17H2,1-2H3,(H,19,20)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.53E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of human ERAP2 preincubated for 30 to 60 mins followed by addition of Arg-AMC as substrate measured for 15 mins by spectrofluorimetric met...				Bioorg Med Chem Lett 26: 4122-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.062 BindingDB Entry DOI: 10.7270/Q2TT4SW1
					More data for this Ligand-Target Pair
Aminopeptidase (Homo sapiens (Human))	BDBM50170881 (CHEMBL3805028) Show SMILES CC(C)CNCC(N)P(O)(=O)CC(Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H27N2O4P/c1-12(2)9-18-10-15(17)23(21,22)11-14(16(19)20)8-13-6-4-3-5-7-13/h3-7,12,14-15,18H,8-11,17H2,1-2H3,(H,19,20)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of human ERAP1 preincubated for 30 to 60 mins followed by addition of Leu-AMC as substrate measured for 15 mins by spectrofluorimetric met...				Bioorg Med Chem Lett 26: 4122-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.062 BindingDB Entry DOI: 10.7270/Q2TT4SW1
					More data for this Ligand-Target Pair