BDBM50170899 CHEMBL3806100

SMILES: NCCNCC(N)P(O)(O)=O

InChI Key: InChIKey=YZZVYJAKRZZYBF-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50170899   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Sus scrofa (Pig))	BDBM50170899 (CHEMBL3806100) Show SMILES NCCNCC(N)P(O)(O)=O Show InChI InChI=1S/C4H14N3O3P/c5-1-2-7-3-4(6)11(8,9)10/h4,7H,1-3,5-6H2,(H2,8,9,10)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.24E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...				Eur J Med Chem 117: 187-96 (2016) BindingDB Entry DOI: 10.7270/Q2BC41F8
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50170899 (CHEMBL3806100) Show SMILES NCCNCC(N)P(O)(O)=O Show InChI InChI=1S/C4H14N3O3P/c5-1-2-7-3-4(6)11(8,9)10/h4,7H,1-3,5-6H2,(H2,8,9,10)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.11E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...				Eur J Med Chem 117: 187-96 (2016) BindingDB Entry DOI: 10.7270/Q2BC41F8
					More data for this Ligand-Target Pair
Aminopeptidase (Homo sapiens (Human))	BDBM50170899 (CHEMBL3806100) Show SMILES NCCNCC(N)P(O)(O)=O Show InChI InChI=1S/C4H14N3O3P/c5-1-2-7-3-4(6)11(8,9)10/h4,7H,1-3,5-6H2,(H2,8,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human ERAP1 using L-AMC as substrate measured for 15 to 30 mins by fluorescence analysis				Bioorg Med Chem Lett 26: 4122-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.062 BindingDB Entry DOI: 10.7270/Q2TT4SW1
					More data for this Ligand-Target Pair
Aminopeptidase (Homo sapiens (Human))	BDBM50170899 (CHEMBL3806100) Show SMILES NCCNCC(N)P(O)(O)=O Show InChI InChI=1S/C4H14N3O3P/c5-1-2-7-3-4(6)11(8,9)10/h4,7H,1-3,5-6H2,(H2,8,9,10)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of human ERAP2 preincubated for 30 to 60 mins followed by addition of Arg-AMC as substrate measured for 15 mins by spectrofluorimetric met...				Bioorg Med Chem Lett 26: 4122-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.062 BindingDB Entry DOI: 10.7270/Q2TT4SW1
					More data for this Ligand-Target Pair
Leucine aminopeptidase (LAP) (Sus scrofa (Pig))	BDBM50170899 (CHEMBL3806100) Show SMILES NCCNCC(N)P(O)(O)=O Show InChI InChI=1S/C4H14N3O3P/c5-1-2-7-3-4(6)11(8,9)10/h4,7H,1-3,5-6H2,(H2,8,9,10)	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.89E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of porcine kidney leucine aminopeptidase M17 using Leu-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition meas...				Eur J Med Chem 117: 187-96 (2016) BindingDB Entry DOI: 10.7270/Q2BC41F8
					More data for this Ligand-Target Pair