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BDBM50170899 CHEMBL3806100

SMILES: NCCNCC(N)P(O)(O)=O

InChI Key: InChIKey=YZZVYJAKRZZYBF-UHFFFAOYNA-N

Data: 5 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50170899   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170899
PNG
(CHEMBL3806100)
Show SMILES NCCNCC(N)P(O)(O)=O
Show InChI InChI=1/C4H14N3O3P/c5-1-2-7-3-4(6)11(8,9)10/h4,7H,1-3,5-6H2,(H2,8,9,10)
PDB

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PC cid
PC sid
UniChem

Similars

PubMed
3.24E+4n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens)
BDBM50170899
PNG
(CHEMBL3806100)
Show SMILES NCCNCC(N)P(O)(O)=O
Show InChI InChI=1/C4H14N3O3P/c5-1-2-7-3-4(6)11(8,9)10/h4,7H,1-3,5-6H2,(H2,8,9,10)
PDB

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UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
4.11E+4n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase


(Homo sapiens)
BDBM50170899
PNG
(CHEMBL3806100)
Show SMILES NCCNCC(N)P(O)(O)=O
Show InChI InChI=1/C4H14N3O3P/c5-1-2-7-3-4(6)11(8,9)10/h4,7H,1-3,5-6H2,(H2,8,9,10)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
>2.50E+5n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human ERAP1 using L-AMC as substrate measured for 15 to 30 mins by fluorescence analysis


Bioorg Med Chem Lett 26: 4122-6 (2016)

More data for this
Ligand-Target Pair
Aminopeptidase


(Homo sapiens)
BDBM50170899
PNG
(CHEMBL3806100)
Show SMILES NCCNCC(N)P(O)(O)=O
Show InChI InChI=1/C4H14N3O3P/c5-1-2-7-3-4(6)11(8,9)10/h4,7H,1-3,5-6H2,(H2,8,9,10)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>2.50E+5n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of human ERAP2 preincubated for 30 to 60 mins followed by addition of Arg-AMC as substrate measured for 15 mins by spectrofluorimetric met...


Bioorg Med Chem Lett 26: 4122-6 (2016)

More data for this
Ligand-Target Pair
Leucine aminopeptidase (LAP)


(Sus scrofa (Pig))
BDBM50170899
PNG
(CHEMBL3806100)
Show SMILES NCCNCC(N)P(O)(O)=O
Show InChI InChI=1/C4H14N3O3P/c5-1-2-7-3-4(6)11(8,9)10/h4,7H,1-3,5-6H2,(H2,8,9,10)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
2.89E+5n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney leucine aminopeptidase M17 using Leu-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition meas...


Citation and Details
More data for this
Ligand-Target Pair