null

SMILES: NN(NC(=S)NCCc1ccc(cc1)S(N)(=O)=O)c1c(F)c(F)c(F)c(F)c1F

InChI Key: InChIKey=UVBRNWRRLAZDRZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50171025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50171025 (CHEMBL182197 | N-{2-[4-(aminosulfonyl)phenyl]ethyl...) Show SMILES NN(NC(=S)NCCc1ccc(cc1)S(N)(=O)=O)c1c(F)c(F)c(F)c(F)c1F Show InChI InChI=1S/C15H14F5N5O2S2/c16-9-10(17)12(19)14(13(20)11(9)18)25(21)24-15(28)23-6-5-7-1-3-8(4-2-7)29(22,26)27/h1-4H,5-6,21H2,(H2,22,26,27)(H2,23,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against catalytic domain of human carbonic anhydrase XII				Bioorg Med Chem Lett 15: 3821-7 (2005) Article DOI: 10.1016/j.bmcl.2005.06.054 BindingDB Entry DOI: 10.7270/Q2H132SW
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50171025 (CHEMBL182197 | N-{2-[4-(aminosulfonyl)phenyl]ethyl...) Show SMILES NN(NC(=S)NCCc1ccc(cc1)S(N)(=O)=O)c1c(F)c(F)c(F)c(F)c1F Show InChI InChI=1S/C15H14F5N5O2S2/c16-9-10(17)12(19)14(13(20)11(9)18)25(21)24-15(28)23-6-5-7-1-3-8(4-2-7)29(22,26)27/h1-4H,5-6,21H2,(H2,22,26,27)(H2,23,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human carbonic anhydrase II				Bioorg Med Chem Lett 15: 3821-7 (2005) Article DOI: 10.1016/j.bmcl.2005.06.054 BindingDB Entry DOI: 10.7270/Q2H132SW
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50171025 (CHEMBL182197 | N-{2-[4-(aminosulfonyl)phenyl]ethyl...) Show SMILES NN(NC(=S)NCCc1ccc(cc1)S(N)(=O)=O)c1c(F)c(F)c(F)c(F)c1F Show InChI InChI=1S/C15H14F5N5O2S2/c16-9-10(17)12(19)14(13(20)11(9)18)25(21)24-15(28)23-6-5-7-1-3-8(4-2-7)29(22,26)27/h1-4H,5-6,21H2,(H2,22,26,27)(H2,23,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human carbonic anhydrase I				Bioorg Med Chem Lett 15: 3821-7 (2005) Article DOI: 10.1016/j.bmcl.2005.06.054 BindingDB Entry DOI: 10.7270/Q2H132SW
					More data for this Ligand-Target Pair