BDBM50171261 3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol::CHEMBL197664

SMILES: CN(C)CCc1cn(C)c2cccc(O)c12

InChI Key: InChIKey=MZZRFEIDRWKTKJ-UHFFFAOYSA-N

Data: 6 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50171261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50171261 (3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...) Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12 Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...				Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50171261 (3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...) Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12 Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...				Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50171261 (3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...) Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12 Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO				Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50171261 (3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...) Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12 Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO				Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50171261 (3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...) Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12 Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO				Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50171261 (3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...) Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12 Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO				Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50171261 (3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...) Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12 Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2C receptor determi...				Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50171261 (3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...) Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12 Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	633	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2A receptor determi...				Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5
					More data for this Ligand-Target Pair