BDBM50171272 3-Dimethylaminomethyl-1H-indol-4-ol::CHEMBL194588

SMILES: CN(C)Cc1c[nH]c2cccc(O)c12

InChI Key: InChIKey=YJJMKVPZBCHYHD-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50171272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50171272 (3-Dimethylaminomethyl-1H-indol-4-ol | CHEMBL194588) Show SMILES CN(C)Cc1c[nH]c2cccc(O)c12 Show InChI InChI=1S/C11H14N2O/c1-13(2)7-8-6-12-9-4-3-5-10(14)11(8)9/h3-6,12,14H,7H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	12.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...				Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50171272 (3-Dimethylaminomethyl-1H-indol-4-ol | CHEMBL194588) Show SMILES CN(C)Cc1c[nH]c2cccc(O)c12 Show InChI InChI=1S/C11H14N2O/c1-13(2)7-8-6-12-9-4-3-5-10(14)11(8)9/h3-6,12,14H,7H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...				Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50171272 (3-Dimethylaminomethyl-1H-indol-4-ol | CHEMBL194588) Show SMILES CN(C)Cc1c[nH]c2cccc(O)c12 Show InChI InChI=1S/C11H14N2O/c1-13(2)7-8-6-12-9-4-3-5-10(14)11(8)9/h3-6,12,14H,7H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO				Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50171272 (3-Dimethylaminomethyl-1H-indol-4-ol | CHEMBL194588) Show SMILES CN(C)Cc1c[nH]c2cccc(O)c12 Show InChI InChI=1S/C11H14N2O/c1-13(2)7-8-6-12-9-4-3-5-10(14)11(8)9/h3-6,12,14H,7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	834	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO				Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50171272 (3-Dimethylaminomethyl-1H-indol-4-ol | CHEMBL194588) Show SMILES CN(C)Cc1c[nH]c2cccc(O)c12 Show InChI InChI=1S/C11H14N2O/c1-13(2)7-8-6-12-9-4-3-5-10(14)11(8)9/h3-6,12,14H,7H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	923	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO				Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50171272 (3-Dimethylaminomethyl-1H-indol-4-ol | CHEMBL194588) Show SMILES CN(C)Cc1c[nH]c2cccc(O)c12 Show InChI InChI=1S/C11H14N2O/c1-13(2)7-8-6-12-9-4-3-5-10(14)11(8)9/h3-6,12,14H,7H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO				Bioorg Med Chem Lett 15: 4555-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.104 BindingDB Entry DOI: 10.7270/Q2PZ58B5
					More data for this Ligand-Target Pair