BDBM50171313 (3-Ethyl-2-methyl-quinolin-6-yl)-(4-methoxy-cyclohexyl)-methanone::CHEMBL188906
SMILES: CCc1cc2cc(ccc2nc1C)C(=O)[C@@H]1CC[C@@H](CC1)OC
InChI Key: InChIKey=VEURHZYLLRSEGL-RHNCMZPLSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor (RAT) | BDBM50171313 ((3-Ethyl-2-methyl-quinolin-6-yl)-(4-methoxy-cycloh...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.870 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description In vitro affinity for cloned rat metabotropic glutamate 1 receptors stably expressed on CHO cells determined using [3H]-R214127 as radioligand | J Med Chem 48: 5096-9 (2005) Article DOI: 10.1021/jm050263+ BindingDB Entry DOI: 10.7270/Q29S1QJK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor (Rattus norvegicus (Rat)) | BDBM50171313 ((3-Ethyl-2-methyl-quinolin-6-yl)-(4-methoxy-cycloh...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description In vitro affinity for cloned rat metabotropic glutamate 5 receptors stably expressed on CHO cells determined in radioligand binding assay | J Med Chem 48: 5096-9 (2005) Article DOI: 10.1021/jm050263+ BindingDB Entry DOI: 10.7270/Q29S1QJK | |||||||||||
More data for this Ligand-Target Pair |