BDBM50171475 CHEMBL190288::{3-[2-(Diphenyl-ethanesulfonyl)-ethyl]-2-hydroxymethyl-benzofuran-7-yloxy}-acetic acid
SMILES: CC(c1ccccc1)(c1ccccc1)S(=O)(=O)CCc1c(CO)oc2c(OCC(O)=O)cccc12
InChI Key: InChIKey=MBZZAZPECJKQCO-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostanoid TP receptor (Homo sapiens (Human)) | BDBM50171475 (CHEMBL190288 | {3-[2-(Diphenyl-ethanesulfonyl)-eth...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]-SQ-29,548 binding to thromboxane A2 receptors (TP) of human platelet membrane | J Med Chem 48: 5279-94 (2005) Article DOI: 10.1021/jm050194z BindingDB Entry DOI: 10.7270/Q2J67GGC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid IP receptor (Homo sapiens (Human)) | BDBM50171475 (CHEMBL190288 | {3-[2-(Diphenyl-ethanesulfonyl)-eth...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]-APS-314d binding to prostacyclin receptors (IP) of human platelet membrane | J Med Chem 48: 5279-94 (2005) Article DOI: 10.1021/jm050194z BindingDB Entry DOI: 10.7270/Q2J67GGC | |||||||||||
More data for this Ligand-Target Pair |