BDBM50171597 5-Chloro-N-(1-naphthalen-2-ylmethyl-piperidin-4-yl)-2-[(thiazol-2-ylmethyl)-amino]-benzamide::CHEMBL194726

SMILES: Clc1ccc(NCc2nccs2)c(c1)C(=O)NC1CCN(Cc2ccc3ccccc3c2)CC1

InChI Key: InChIKey=QXOVDVVHABLTCE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171597   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50171597 (5-Chloro-N-(1-naphthalen-2-ylmethyl-piperidin-4-yl...) Show SMILES Clc1ccc(NCc2nccs2)c(c1)C(=O)NC1CCN(Cc2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C27H27ClN4OS/c28-22-7-8-25(30-17-26-29-11-14-34-26)24(16-22)27(33)31-23-9-12-32(13-10-23)18-19-5-6-20-3-1-2-4-21(20)15-19/h1-8,11,14-16,23,30H,9-10,12-13,17-18H2,(H,31,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against MCH1R IMR32 cells in FLIPR-based assay				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50171597 (5-Chloro-N-(1-naphthalen-2-ylmethyl-piperidin-4-yl...) Show SMILES Clc1ccc(NCc2nccs2)c(c1)C(=O)NC1CCN(Cc2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C27H27ClN4OS/c28-22-7-8-25(30-17-26-29-11-14-34-26)24(16-22)27(33)31-23-9-12-32(13-10-23)18-19-5-6-20-3-1-2-4-21(20)15-19/h1-8,11,14-16,23,30H,9-10,12-13,17-18H2,(H,31,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity towards melanin-concentrating hormone receptor 1 in IMR32 cells				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair